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Publications (Research articles)

Publications in English

2018

  1. Kuroda M, Sekizuka T, Matsui H, Suzuki K, Seki H, Saito M, Hanaki H.
    Complete Genome Sequence and Characterization of Linezolid-Resistant Enterococcus faecalis Clinical Isolate KUB3006 Carrying a cfr(B)-Transposon on Its Chromosome and optrA-Plasmid. Front Microbiol. 2018 Oct 25;9:2576. doi: 10.3389/fmicb.2018.02576. eCollection 2018.
  2. Uchiyama J, Matsui H, Murakami H, Kato SI, Watanabe N, Nasukawa T, Mizukami K, Ogata M, Sakaguchi M, Matsuzaki S, Hanaki H.
    Potential Application of Bacteriophages in Enrichment Culture for Improved Prenatal Streptococcus agalactiae Screening. Viruses. 2018 Oct 10;10(10). pii: E552. doi: 10.3390/v10100552.
  3. Kinoshita Y, Yakushiji F, Matsui H, Hanaki H, Ichikawa S. Study of the structure-activity relationship of polymyxin analogues. Bioorg Med Chem Lett. 2018 Mar 22. pii: S0960-894X(18)30207-5.
  4. Yamada T, Yagita M, Kobayashi Y, Sennari G, Shimamura H, Matsui H, Horimatsu Y, Hanaki H, Hirose T, O Mura S, Sunazuka T. Synthesis and Evaluation of Antibacterial Activity of Bottromycins. J Org Chem. 2018 Apr 16. doi: 10.1021/acs.joc.8b00045. [Epub ahead of print] PubMed
  5. Takesue Y, Kusachi S, Mikamo H, Sato J, Watanabe A, Kiyota H, Iwata S, Kaku M, Hanaki H, Sumiyama Y, Kitagawa Y, Nakajima K, Ueda T, Uchino M, Mizuguchi T, Ambo Y, Konosu M, Ishibashi K, Matsuda A, Hase K, Harihara Y, Okabayashi K, Seki S, Hara T, Matsui K, Matsuo Y, Kobayashi M, Kubo S, Uchiyama K, Shimizu J, Kawabata R, Ohge H, Akagi S, Oka M, Wakatsuki T, Suzuki K, Okamoto K, Yanagihara K. Antimicrobial susceptibility of common pathogens isolated from postoperative intra-abdominal infections in Japan. J Infect Chemother. 2018 May;24(5):330-340.
  6. Asakura K, Azechi T, Sasano H, Matsui H, Hanaki H, Miyazaki M, Takata T, Sekine M, Takaku T, Ochiai T, Komatsu N, Shibayama K, Katayama Y, Yahara K. Rapid and easy detection of low-level resistance to vancomycin in methicillin-resistant Staphylococcus aureus by matrix-assisted laser desorption ionization time-of-flight mass spectrometry. PLoS One. 2018 Mar 9;13(3):e0194212.
  7. Tanaka J, Hirayama F, Yanase S, Uno S, Nakae T, Kamizono A, Hanaki H. Effective concentration of intravenous immunoglobulin for neutralizing Panton-Valentine leukocidin in human blood. J Infect Chemother. 2018 May;24(5):383-388.
  8. Sakata H, Sato Y, Toyonaga Y, Hanaki H; Drug-Resistant Pathogen Surveillance Group in Pediatric Infectious Disease. Serotype replacement of Streptococcus pneumoniae due to seven-valent pneumococcal conjugate vaccine in Japan. Pediatr Int. 2018 Jan;60(1):52-56.

2017

  1. Takesue Y, Kusachi S, Mikamo H, Sato J, Watanabe A, Kiyota H, Iwata S, Kaku M, Hanaki H, Sumiyama Y, Kitagawa Y, Mizuguchi T, Ambo Y, Konosu M, Ishibashi K, Matsuda A, Hase K, Harihara Y, Okabayashi K, Seki S, Hara T, Matsui K, Matsuo Y, Kobayashi M, Kubo S, Uchiyama K, Shimizu J, Kawabata R, Ohge H, Akagi S, Oka M, Wakatsuki T, Suzuki K, Okamoto K, Yanagihara K. Corrigendum to 'Antimicrobial susceptibility of pathogens isolated from surgical site infections in Japan: Comparison of data from nationwide surveillance studies conducted in 2010 and 2014-2015' [J Infect Chemother 23 (2017) 339-348]. J Infect Chemother. 2018 Feb;24(2):156-157.
  2. Sato T, Usui M, Konishi N, Kai A, Matsui H, Hanaki H, Tamura Y. Closely related methicillin-resistant Staphylococcus aureus isolates from retail meat, cows with mastitis, and humans in Japan. PLoS One. 2017 Oct 30;12(10):e0187319.
  3. Ono T, Nejima R, Iwasaki T, Mori Y, Noguchi Y, Yagi A, Hanaki H, Miyata K. Long-term effects of cataract surgery with topical levofloxacin on ocular bacterial flora. J Cataract Refract Surg. 2017 Sep;43(9):1129-1134.
  4. Katayama Y, Azechi T, Miyazaki M, Takata T, Sekine M, Matsui H, Hanaki H, Yahara K, Sasano H, Asakura K, Takaku T, Ochiai T, Komatsu N, Chambers HF. Prevalence of Slow-Growth Vancomycin Nonsusceptibility in Methicillin-Resistant Staphylococcus aureus. Antimicrob Agents Chemother. 2017 Oct 24;61(11). pii: e00452-17.
  5. Takayama Y, Matsui H, Adachi Y, Nihonyanagi S, Wada T, Mochizuki J, Unno N, Hanaki H. Detection of Streptococcus agalactiae by immunochromatography with group B streptococcus-specific surface immunogenic protein in pregnant women. J Infect Chemother. 2017 Oct;23(10):678-682.
  6. Watanabe S, Ohnishi T, Yuasa A, Kiyota H, Iwata S, Kaku M, Watanabe A, Sato J,
    Hanaki H, Manabe M, Suzuki T, Otsuka F, Aihara M, Iozumi K, Tamaki T, Funada Y,
    Shinozaki M, Kobayashi M, Okuda M, Kikyo G, Kikuchi K, Okada Y, Takeshima M,
    Kaneko O, Ogawa N, Ito R, Okuyama R, Shimada S, Shimizu T, Hatta N, Manabu M,
    Tsutsui K, Tanaka T, Miyachi Y, Asada H, Furukawa F, Kurokawa I, Iwatsuki K, Hide
    M, Muto M, Yamamoto O, Niihara H, Takagaki K, Kubota Y, Sayama K, Sano S, Furue
    M, Kanekura T. The first nationwide surveillance of antibacterial susceptibility
    patterns of pathogens isolated from skin and soft-tissue infections in
    dermatology departments in Japan. J Infect Chemother. 2017 Aug;23(8):503-511.
  7. Sugawara A, Maruyama H, Shibusawa S, Matsui H, Hirose T, Tsutsui A, Froyman R, Ludwig C, Koebberling J, Hanaki H, Kleefeld G, Ōmura S, Sunazuka T. 5-O-Mycaminosyltylonolide antibacterial derivatives: design, synthesis and bioactivity. J Antibiot (Tokyo). 2017 Jul;70(8):878-887.
  8. Yanagihara K, Watanabe A, Aoki N, Matsumoto T, Yoshida M, Sato J, Wakamura T,
    Sunakawa K, Kadota J, Kiyota H, Iwata S, Kaku M, Hanaki H, Ohsaki Y, Fujiuchi S,
    Takahashi M, Takeuchi K, Takeda H, Ikeda H, Miki M, Nakanowatari S, Takahashi H,
    Utagawa M, Nishiya H, Kawakami S, Morino E, Takasaki J, Mezaki K, Chonabayashi N, Tanaka C, Sugiura H, Goto H, Saraya T, Kurai D, Katono Y, Inose R, Niki Y, Takuma
    T, Kudo M, Ehara S, Sato Y, Tsukada H, Watabe N, Honma Y, Mikamo H, Yamagishi Y,
    Nakamura A, Ohashi M, Seki M, Hamaguchi S, Toyokawa M, Fujikawa Y, Mitsuno N,
    Ukimura A, Miyara T, Nakamura T, Mikasa K, Kasahara K, Ui K, Fukuda S, Nakamura
    A, Morimura M, Yamashita M, Takesue Y, Wada Y, Sugimoto K, Kusano N, Nose M,
    Mihara E, Kuwabara M, Doi M, Watanabe Y, Tokuyasu H, Hino S, Negayama K, Mukae H, Kawanami T, Ota T, Fujita M, Honda J, Hiramatsu K, Aoki Y, Fukuoka M, Magarifuchi H, Nagasawa Z, Kaku N, Fujita J, Higa F, Tateyama M. Nationwide surveillance of bacterial respiratory pathogens conducted by the surveillance committee of Japanese Society of Chemotherapy, the Japanese Association for Infectious Diseases, and the Japanese Society for Clinical Microbiology in 2012: General view of the pathogens' antibacterial susceptibility. J Infect Chemother. 2017 Jun 29. pii: S1341-321X(17)30133-2.
  9. Takesue Y, Kusachi S, Mikamo H, Sato J, Watanabe A, Kiyota H, Iwata S, Kaku M,
    Hanaki H, Sumiyama Y, Kitagawa Y, Mizuguchi T, Ambo Y, Konosu M, Ishibashi K,
    Matsuda A, Hase K, Harihara Y, Okabayashi K, Seki S, Hara T, Matsui K, Matsuo Y,
    Kobayashi M, Kubo S, Uchiyama K, Shimizu J, Kawabata R, Ohge H, Akagi S, Oka M,
    Wakatsuki T, Suzuki K, Okamoto K, Yanagihara K. Antimicrobial susceptibility of
    pathogens isolated from surgical site infections in Japan: Comparison of data
    from nationwide surveillance studies conducted in 2010 and 2014-2015. J Infect
    Chemother. 2017 Jun;23(6):339-348.
  10. Fukumoto A, Kim YP, Matsumoto A, Takahashi Y, Suzuki M, Onodera H, Tomoda H,
    Matsui H, Hanaki H, Iwatsuki M, Ōmura S, Shiomi K. Naphthacemycins, novel
    circumventors of β-lactam resistance in MRSA, produced by Streptomyces sp.
    KB-3346-5. I. The taxonomy of the producing strain, and the fermentation,
    isolation and antibacterial activities. J Antibiot (Tokyo). 2017
    May;70(5):562-567.
  11. Fukumoto A, Kim YP, Iwatsuki M, Hirose T, Sunazuka T, Hanaki H, Ōmura S,
    Shiomi K. Naphthacemycins, novel circumventors of β-lactam resistance in MRSA,
    produced by Streptomyces sp. KB-3346-5. II. Structure elucidation. J Antibiot
    (Tokyo). 2017 May;70(5):568-573.
  12. Hirose T, Kojima Y, Matsui H, Hanaki H, Iwatsuki M, Shiomi K, Ōmura S,
    Sunazuka T. Total synthesis of (±)-naphthacemycin A(9), possessing both
    antibacterial activity against methicillin-resistant Staphylococcus aureus and
    circumventing effect of β-lactam resistance. J Antibiot (Tokyo). 2017
    May;70(5):574-581.

2016

  1. Takahashi S, Hamasuna R, Yasuda M, Ishikawa K, Hayami H, Uehara S, Yamamoto S, Minamitani S, Kadota J, Iwata S, Kaku M, Watanabe A, Sato J, Hanaki H, Masumori
    N, Kiyota H, Egawa S, Tanaka K, Arakawa S, Fujisawa M, Kumon H, Wada K, Kobayashi K, Matsubara A, Matsumoto T, Eto M, Tatsugami K, Kuroiwa K, Ito K, Hosobe T, Hirayama H, Narita H, Yamaguchi T, Ito S, Sumii T, Kawai S, Kanokogi M, Kawano H, Chokyu H, Uno S, Monden K, Kaji S, Kawahara M, Takayama K, Ito M, Yoshioka M, Kano M, Konishi T, Kadena H, Nishi S, Nishimura H, Yamauchi T, Maeda S, Horie M, Ihara H, Matsumura M, Shirane T, Takeyama K, Akiyama K, Takahashi K, Ikuyama T, Inatomi H, Yoh M. Nationwide surveillance of the antimicrobial susceptibility of Chlamydia trachomatis from male urethritis in Japan. J Infect Chemother. 2016 Sep;22(9):581-6. 27452428.
  2. Suga T, Shiina M, Asami Y, Iwatsuki M, Yamamoto T, Nonaka K, Masuma R, Matsui
    H, Hanaki H, Iwamoto S, Onodera H, Shiomi K, Ōmura S. Paraphaeosphaeride D and
    berkleasmin F, new circumventors of arbekacin resistance in MRSA, produced by
    Paraphaeosphaeria sp. TR-022. J Antibiot (Tokyo). 2016 Aug;69(8):605-10.
  3. Hirai J, Hagihara M, Kato H, Sakanashi D, Nishiyama N, Koizumi Y, Yamagishi
    Y, Suematsu H, Hanaki H, Mikamo H. Investigation on rifampicin administration
    from the standpoint of pharmacokinetics/pharmacodynamics in a neutropenic murine
    thigh infection model. J Infect Chemother. 2016 Jun;22(6):387-94.
  4. Sugawara A, Shima H, Sueki A, Hirose T, Matsui H, Nakano H, Hanaki H, Akagawa
    KS, Ōmura S, Sunazuka T. Non-antibiotic 12-membered macrolides: design, synthesis
    and biological evaluation in a cigarette-smoking model. J Antibiot (Tokyo). 2016
    Apr;69(4):319-26.
  5. Okada T, Sato Y, Toyonaga Y, Hanaki H, Sunakawa K. Nationwide survey of
    Streptococcus pneumoniae drug resistance in the pediatric field in Japan. Pediatr
    Int. 2016 Mar;58(3):192-201.

2015

  1. Ishikawa K, Hamasuna R, Uehara S, Yasuda M, Yamamoto S, Hayami H, Takahashi
    S, Matsumoto T, Minamitani S, Kadota J, Iwata S, Kaku M, Watanabe A, Sunakawa K,
    Sato J, Hanaki H, Tsukamoto T, Kiyota H, Egawa S, Deguchi T, Matsumoto M, Tanaka
    K, Arakawa S, Fujisawa M, Kumon H, Kobayashi K, Matsubara A, Wakeda H, Amemoto Y, Onodera S, Goto H, Komeda H, Yamashita M, Takenaka T, Fujimoto Y, Tsugawa M,
    Takahashi Y, Maeda H, Onishi H, Ishitoya S, Nishimura K, Mitsumori K, Ito T, Togo
    Y, Nakamura I, Ito N, Kanamaru S, Hirose T, Muranaka T, Yamada D, Ishihara S, Oka
    H, Inatomi H, Matsui T, Kobuke M, Kunishima Y, Kimura T, Ichikawa T, Kagara I,
    Matsukawa M, Takahashi K, Mita K, Kato M, Okumura K, Kawanishi H, Hashimura T,
    Aoyama T, Shigeta M, Koda S, Taguchi K, Matsuda Y. Japanese nationwide surveillance in 2011 of antibacterial susceptibility patterns of clinical isolates from complicated urinary tract infection cases. J Infect Chemother. 2015 Sep;21(9):623-33.
  2. Masaki K, Ishii M, Anraku M, Namkoong H, Miyakawa R, Nakajima T, Fukunaga K,
    Naoki K, Tasaka S, Soejima K, Sayama K, Sugita K, Iwata S, Cui L, Hanaki H,
    Hasegawa N, Betsuyaku T. Fatal Fulminant Pneumonia Caused by
    Methicillin-Sensitive Staphylococcus aureus Negative for Major High-Virulence
    Factors Following Influenza B Virus Infection. Am J Case Rep. 2015 Jul
    14;16:454-8.
  3. Suzuki K, Kurono Y, Ikeda K, Watanabe A, Iwamoto A, Totsuka K, Kaku M, Iwata
    S, Kadota J, Hanaki H. Nationwide surveillance of 6 otorhinolaryngological
    infectious diseases and antimicrobial susceptibility pattern in the isolated
    pathogens in Japan. J Infect Chemother. 2015 Jul;21(7):483-91.
  4. Ikeda-Dantsuji Y, Hanaki H, Sakai F, Tomono K, Takesue Y, Honda J, Nonomiya
    Y, Suwabe A, Nagura O, Yanagihara K, Mikamo H, Fukuchi K, Kaku M, Kohno S,
    Yanagisawa C, Nakae T, Yoshida K, Niki Y. Linezolid-resistant Staphylococcus
    aureus isolated from 2006 through 2008 at six hospitals in Japan. Kansenshogaku
    Zasshi. 2015 Jul;Suppl 13:8-14.
  5. Yanagihara K, Kadota J, Aoki N, Matsumoto T, Yoshida M, Yagisawa M, Oguri T,
    Sato J, Ogasawara K, Wakamura T, Sunakawa K, Watanabe A, Iwata S, Kaku M, Hanaki
    H, Ohsaki Y, Watari T, Toyoshima E, Takeuchi K, Shiokoshi M, Takeda H, Miki M,
    Kumagai T, Nakanowatari S, Takahashi H, Utagawa M, Nishiya H, Kawakami S,
    Kobayashi N, Takasaki J, Mezaki K, Konosaki H, Aoki Y, Yamamoto Y, Shoji M, Goto
    H, Saraya T, Kurai D, Okazaki M, Niki Y, Yoshida K, Kawana A, Saionji K, Fujikura
    Y, Miyazawa N, Kudo M, Sato Y, Yamamoto M, Yoshida T, Nakamura M, Tsukada H, Imai Y, Tsukada A, Kawasaki S, Honma Y, Yamamoto T, Ban N, Mikamo H, Sawamura H, Miyara T, Toda H, Sato K, Nakamura T, Fujikawa Y, Mitsuno N, Mikasa K, Kasahara
    K, Sano R, Sugimoto K, Asari S, Nishi I, Toyokawa M, Miyashita N, Koguchi Y,
    Kusano N, Mihara E, Kuwabara M, Watanabe Y, Kawasaki Y, Takeda K, Tokuyasu H,
    Masui K, Negayama K, Hiramatsu K, Aoki Y, Fukuoka M, Magarifuchi H, Nagasawa Z,
    Suga M, Muranaka H, Morinaga Y, Honda J, Fujita M. Nationwide surveillance of
    bacterial respiratory pathogens conducted by the surveillance committee of
    Japanese Society of Chemotherapy, the Japanese Association for Infectious
    Diseases, and the Japanese Society for Clinical Microbiology in 2010: General
    view of the pathogens' antibacterial susceptibility. J Infect Chemother. 2015
    Jun;21(6):410-20.
  6. Hamasuna R, Yasuda M, Ishikawa K, Uehara S, Hayami H, Takahashi S, Matsumoto
    T, Yamamoto S, Minamitani S, Watanabe A, Iwata S, Kaku M, Kadota J, Sunakawa K,
    Sato J, Hanaki H, Tsukamoto T, Kiyota H, Egawa S, Tanaka K, Arakawa S, Fujisawa
    M, Kumon H, Kobayashi K, Matsubara A, Naito S, Kuroiwa K, Hirayama H, Narita H,
    Hosobe T, Ito S, Ito K, Kawai S, Ito M, Chokyu H, Matsumura M, Yoshioka M, Uno S,
    Monden K, Takayama K, Kaji S, Kawahara M, Sumii T, Kadena H, Yamaguchi T, Maeda
    S, Nishi S, Nishimura H, Shirane T, Yoh M, Akiyama K, Imai T, Kano M. The second
    nationwide surveillance of the antimicrobial susceptibility of Neisseria
    gonorrhoeae from male urethritis in Japan, 2012-2013. J Infect Chemother. 2015
    May;21(5):340-5.
  7. Baba H, Sato Y, Toyonaga Y, Hanaki H, Sunakawa K. Nationwide survey of the
    development of drug resistance in the pediatric field in 2007, 2010, and 2012:
    drug sensitivity of Haemophilus influenzae serotype b strain in Japan. J Infect
    Chemother. 2015 Apr;21(4):277-83.
  8. Shiro H, Sato Y, Toyonaga Y, Hanaki H, Sunakawa K. Nationwide survey of the
    development of drug resistance in the pediatric field in 2000-2001, 2004, 2007,
    2010, and 2012: evaluation of the changes in drug sensitivity of Haemophilus
    influenzae and patients' background factors. J Infect Chemother. 2015
    Apr;21(4):247-56.
  9. Iwata S, Sato Y, Toyonaga Y, Hanaki H, Sunakawa K. Genetic analysis of a
    pediatric clinical isolate of Moraxella catarrhalis with resistance to macrolides
    and quinolones. J Infect Chemother. 2015 Apr;21(4):308-11.
  10. Nihonyanagi S, Sunakawa K, Cui L, Masaki T, Wada T, Hoshiyama T, Nakamura M,
    Takayama Y, Kanoh Y, Ogawa A, Shichiri M, Hanaki H. A very rare case of primary
    meningococcal arthritis in an adult male. Clin Case Rep. 2015 Feb;3(2):76-80.
  11. Shoji H, Maeda M, Shirakura T, Takuma T, Hanaki H, Niki Y. Changes in the
    Distribution of Capsular Serotypes of Streptococcus pneumoniae Isolated from
    Adult Respiratory Specimens in Japan. Intern Med. 2015;54(11):1337-41.

2014

  1. Uchida R, Hanaki H, Matsui H, Hamamoto H, Sekimizu K, Iwatsuki M, Kim YP,
    Tomoda H. In vitro and in vivo anti-MRSA activities of nosokomycins. Drug Discov
    Ther. 2014 Dec;8(6):249-54.
  2. Hanaki H, Cui L, Ikeda-Dantsuji Y, Nakae T, Honda J, Yanagihara K, Takesue Y,
    Matsumoto T, Sunakawa K, Kaku M, Tomono K, Fukuchi K, Kusachi S, Mikamo H, Takata T, Otsuka Y, Nagura O, Fujitani S, Aoki Y, Yamaguchi Y, Tateda K, Kadota J, Kohno S, Niki Y. Antibiotic susceptibility survey of blood-borne MRSA isolates in Japan
    from 2008 through 2011. J Infect Chemother. 2014 Sep;20(9):527-34.
  3. Shoji H, Shirakura T, Fukuchi K, Takuma T, Hanaki H, Tanaka K, Niki Y. A
    molecular analysis of quinolone-resistant Haemophilus influenzae: validation of
    the mutations in Quinolone Resistance-Determining Regions. J Infect Chemother.
    2014 Apr;20(4):250-5.
  4. Uchiyama J, Takemura-Uchiyama I, Kato S, Sato M, Ujihara T, Matsui H, Hanaki
    H, Daibata M, Matsuzaki S. In silico analysis of AHJD-like viruses,
    Staphylococcus aureus phages S24-1 and S13', and study of phage S24-1 adsorption.
    Microbiologyopen. 2014 Apr;3(2):257-70.

2013

  1. Takata K, Iwatsuki M, Yamamoto T, Shirahata T, Nonaka K, Masuma R, Hayakawa Y, Hanaki H, Kobayashi Y, Petersson GA, Omura S, Shiomi K. Aogacillins A and B Produced by Simplicillium sp. FKI-5985: New Circumventors of Arbekacin Resistance in MRSA. Org Lett. 2013 Sep 20;15(18):4678-4681. Epub 2013 Sep 4.
  2. Hamasuna R, Yasuda M, Ishikawa K, Uehara S, Takahashi S, Hayami H, Yamamoto S, Matsumoto T, Minamitani S, Watanabe A, Iwamoto A, Totsuka K, Kadota J, Sunakawa K, Sato J, Hanaki H, Tsukamoto T, Kiyota H, Egawa S, Tanaka K, Arakawa S, Fujisawa M, Kumon H, Kobayashi K, Matsubara A, Naito S, Tatsugami K, Ito S, Narita H, Kanokogi M, Sumii T, Ito K, Hosobe T, Kawai S, Kawano H, Takayama K, Yamaguchi T, Endo K, Yamauchi T, Maeda S, Yoh M, Horie M, Ito M, Chokyu H, Ihara H, Akiyama K, Uno S, Monden K, Kaji S, Nishimura H, Kawahara M, Sato T, Konishi T, Nishi S, Ishihara S, Yoshioka M. Nationwide surveillance of the antimicrobial susceptibility of Neisseria gonorrhoeae from male urethritis in Japan. J Infect Chemother. 2013 Aug;19(4):571-8. doi: 10.1007/s10156-013-0637-2. Epub 2013 Jun 28.
  3. Hayami H, Takahashi S, Ishikawa K, Yasuda M, Yamamoto S, Uehara S, Hamasuna R, Matsumoto T, Minamitani S, Watanabe A, Iwamoto A, Totsuka K, Kadota J, Sunakawa K, Sato J, Hanaki H, Tsukamoto T, Kiyota H, Egawa S, Tanaka K, Arakawa S, Fujisawa M, Kumon H, Kobayashi K, Matsubara A, Naito S, Tatsugami K, Yamaguchi T, Ito S, Kanokogi M, Narita H, Kawano H, Hosobe T, Takayama K, Sumii T, Fujii A, Sato T, Yamauchi T, Izumitani M, Chokyu H, Ihara H, Akiyama K, Yoshioka M, Uno S, Monden K, Kano M, Kaji S, Kawai S, Ito K, Inatomi H, Nishimura H, Ikuyama T, Nishi S, Takahashi K, Kawano Y, Ishihara S, Tsuneyoshi K, Matsushita S, Yamane T, Hirose T, Fujihiro S, Endo K, Oka Y, Takeyama K, Kimura T, Uemura T. Nationwide surveillance of bacterial pathogens from patients with acute uncomplicated cystitis conducted by the Japanese surveillance committee during 2009 and 2010: antimicrobial susceptibility of Escherichia coli and Staphylococcus saprophyticus. J Infect Chemother. 2013 Jun;19(3):393-403. doi: 10.1007/s10156-013-0606-9. Epub 2013 May 3.
  4. Hidehito MATSUI, Juri KIMURA, Masato HIGASHIDE, Yoshio TAKEUCHI, Kuniyuki OKUE, Longzhu CUI, Taiji NAKAE, Keisuke SUNAKAWA, Hideaki HANAKI. Immunochromatographic detection of the Group B streptococcus antigen from enrichment cultures. Clin. Vaccine Immunol. 2013 July, 2013;20 1381-1387.
  5. Tajima T, Sato Y, Toyonaga Y, Hanaki H, Sunakawa K. Nationwide survey of the development of drug-resistant pathogens in the pediatric field in 2007 and 2010: drug sensitivity of Streptococcus pneumoniae in Japan (second report). J Infect Chemother. 2013 Apr 7. DOI 10.1007/s10156-013-0593-x. [Epub ahead of print].
  6. Hoshino T, Sato Y, Toyonaga Y, Hanaki H, Sunakawa K; The Drug-Resistant Pathogen Surveillance Group in Pediatric Infectious Disease. Nationwide survey of the development of drug resistance in the pediatric field in 2007 and 2010: drug sensitivity of Haemophilus influenzae in Japan (second report). J Infect Chemother. 2013 Apr 7. DOI 10.1007/s10156-013-0591-z [Epub ahead of print]
  7. Matsumoto T, Hanaki H, Kimura T, Nemoto M, Higashihara M, Yokota H, Oda S, Akiyama N, Miyao N, Yoshida M, Yukioka T, Soma K, Ohyashiki K, Suzuki Y, Arai T, Ikegami K, Ichiwata T, Otsuka Y, Kobayashi M, Totsuka K, Sunakawa K; ABK Dose Finding Study Group. Clinical efficacy and safety of arbekacin sulfate in patients with MRSA sepsis or pneumonia: a multi-institutional study. J Infect Chemother. 2013 19:128–137.
  8. Tsutsui A, Hirose T, Ishiyama A, Iwatsuki M, Yokota A, Maruyama H, Matsui H, Otoguro K, Hanaki H, Omura S, Sunazuka T. Antimalarial C-9 oxime derivatives from desmycosin, produced by click chemistry.  The Journal of Antibiotics (2013) 66, 191–194.

2012

  1. Matsumoto T, Hanaki H, Kimura T, Nemoto M, Higashihara M, Yokota H, Oda S, Akiyama N, Miyao N, Yoshida M, Yukioka T, Soma K, Ohyashiki K, Suzuki Y, Arai T, Ikegami K, Ichiwata T, Otsuka Y, Kobayashi M, Totsuka K, Sunakawa K; ABK Dose Finding Study Group. Clinical efficacy and safety of arbekacin sulfate in patients with MRSA sepsis or pneumonia: a multi-institutional study. J Infect Chemother. 2012 Dec 22. [Epub ahead of print].
  2. Takesue Y, Watanabe A, Hanaki H, Kusachi S, Matsumoto T, Iwamoto A, Totsuka K, Sunakawa K, Yagisawa M, Sato J, Oguri T, Nakanishi K, Sumiyama Y, Kitagawa Y, Wakabayashi G, Koyama I, Yanaga K, Konishi T, Fukushima R, Seki S, Imai S, Shintani T, Tsukada H, Tsukada K, Omura K, Mikamo H, Takeyama H, Kusunoki M, Kubo S, Shimizu J, Hirai T, Ohge H, Kadowaki A, Okamoto K, Yanagihara K. Nationwide surveillance of antimicrobial susceptibility patterns of pathogens isolated from surgical site infections (SSI) in Japan. J Infect Chemother. 2012 Dec;18(6):816-26. doi: 10.1007/s10156-012-0509-1. Epub 2012 Nov 10.
  3. Suga T, Ishii T, Iwatsuki M, Yamamoto T, Nonaka K, Masuma R, Matsui H, Hanaki H, Omura S, Shiomi K. Aranorosin circumvents arbekacin-resistance in MRSA by inhibiting the bifunctional enzyme AAC(6')/APH(2″). J Antibiot (Tokyo). 2012 Oct;65(10):527-9.
  4. Yuriko Hirao, Yurika Ikeda-Dantsuji, Hidehito Matsui, Masaki Yoshida, Seiji Hori, Keisuke Sunakawa , Taiji Nakae, and Hideaki Hanaki. Low level ß-lactamase production in methicillin-resistant Staphylococcus aureus with ß-lactam-antibiotic-induced vancomycin resistance. BMC Microbiol. 2012 May 8;12(1):69.
  5. Watanabe A, Yanagihara K, Matsumoto T, Kohno S, Aoki N, Oguri T, Sato J, Muratani T, Yagisawa M, Ogasawara K, Koashi N, Kozuki T, Komoto A, Takahashi Y, Tsuji T, Terada M, Nakanishi K, Hattori R, Hirako Y, Maruo A, Minamitani S, Morita K, Wakamura T, Sunakawa K, Hanaki H, Ohsaki Y, Honda Y, Sasaoka S, Takeda H, Ikeda H, Sugai A, Miki M, Nakanowatari S, Takahashi H, Utagawa M, Kobayashi N, Takasaki J, Konosaki H, Aoki Y, Shoji M, Goto H, Saraya T, Kurai D, Okazaki M, Kobayashi Y, Katono Y, Kawana A, Saionji K, Miyazawa N, Sato Y, Watanuki Y, Kudo M, Ehara S, Tsukada H, Imai Y, Watabe N, Aso S, Honma Y, Mikamo H, Yamagishi Y, Takesue Y, Wada Y, Nakamura T, Mitsuno N, Mikasa K, Kasahara K, Uno K, Sano R, Miyashita N, Kurokawa Y, Takaya M, Kuwabara M, Watanabe Y, Doi M, Shimizu S, Negayama K, Kadota J, Hiramatsu K, Morinaga Y, Honda J, Fujita M, Iwata S, Iwamoto A, Ezaki T, Onodera S, Kusachi S, Tateda K, Tanaka M, Totsuka K, Niki Y, Matsumoto T. Nationwide surveillance of bacterial respiratory pathogens conducted by the Surveillance Committee of Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Clinical Microbiology in 2009: general view of the pathogens' antibacterial susceptibility. J Infect Chemother. 2012 Jul 6. [Epub ahead of print]
  6. Yurika Ikeda-Dantsuji, Taiji Nakae, Koichi Ariyoshi, Hidekazu Mizuno, Hidehiko Moriyama, Osanori Nagura, Akira Suwabe, Kunihiko Fukuchi, Junichi Honda, Mitsuo Kaku, Shigeru Kohno, Hiroshige Mikamo, Yoshihito Niki, Yoshio Takesue, Kazunori Tomono, Katsunori Yanagihara, and Hideaki Hanaki. Limited detectability of linezolid-resistant Staphylococcus aureus by the Etest method and its improvement using enriched media. J Med Microbiol. 2012 Jul;61(Pt 7):998-1002. Epub 2012 Apr 5.

2011

  1. Masato Iwatsuki, Toshiya Ishimori, Tsuyoshi Yamamoto, Keiko Takata, Mihoko Mori, Kenichi Nonaka, Rokuro Masuma, Yoichi Hayakawa, Hideaki Hanaki, Kazuro Shiomi , Satoshi _Omura a. Biverlactones AeD, new circumventors of arbekacin resistance in MRSA, produced by Penicillium sp. FKI-4429. Tetrahedron 67 (2011) 6644-6648.
  2. Niki Y, Hanaki H, Matsumoto T, Yagisawa M, Kohno S, Aoki N, Watanabe A, Sato J, Hattori R, Koashi N, Terada M, Kozuki T, Maruo A, Morita K, Ogasawara K, Takahashi Y, Matsuda K, Nakanishi K, Sunakawa K, Takeuchi K, Fujimura S, Takeda H, Ikeda H, Sato N, Niitsuma K, Saito M, Koshiba S, Kaneko M, Miki M, Nakanowatari S, Takahashi H, Utagawa M, Nishiya H, Kawakami S, Aoki Y, Chonabayashi N, Sugiura H, Ichioka M, Goto H, Kurai D, Saraya T, Okazaki M, Yoshida K, Yoshida T, Tsukada H, Imai Y, Honma Y, Yamamoto T, Kawai A, Mikamo H, Takesue Y, Wada Y, Miyara T, Toda H, Mitsuno N, Fujikawa Y, Nakajima H, Kubo S, Ohta Y, Mikasa K, Kasahara K, Koizumi A, Sano R, Yagi S, Takaya M, Kurokawa Y, Kusano N, Mihara E, Nose M, Kuwabara M, Fujiue Y, Ishimaru T, Matsubara N, Kawasaki Y, Tokuyasu H, Masui K, Kido M, Ota T, Honda J, Kadota J, Hiramatsu K, Aoki Y, Nagasawa Z, Yanagihara K, Fujita J, Tateyama M, Totsuka K. Nationwide surveillance of bacterial respiratory pathogens conducted by the Japanese Society of Chemotherapy in 2008: general view of the pathogens' antibacterial susceptibility. J Infect Chemother. 2011 Mar 17(4):510-23.
  3. Ikeda-Dantsuji Y, Hanaki H, Nakae T, Takesue Y, Tomono K, Honda J, Yanagihara K, Mikamo H, Fukuchi K, Kaku M, Kohno S, Niki Y.  Emergence of linezolid-resistant mutants in the susceptible cell population of methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother. 2011 May,55(5):2466-8.
  4. Ishikawa K, Matsumoto T, Yasuda M, Uehara S, Muratani T, Yagisawa M, Sato J, Niki Y, Totsuka K, Sunakawa K, Hanaki H, Hattori R, Terada M, Kozuki T, Maruo A, Morita K, Ogasawara K, Takahashi Y, Matsuda K, Hirose T, Miyao N, Hayashi T, Takeyama K, Kiyota H, Tomita M, Yusu H, Koide H, Kimura S, Yanaoka M, Sato H, Ito T, Deguchi T, Fujimoto Y, Komeda H, Asano Y, Takahashi Y, Ishihara S, Arakawa S, Nakano Y, Tanaka K, Fujisawa M, Matsui T, Fujii A, Yamamoto S, Nojima M, Higuchi Y, Ueda Y, Kanamaru S, Monden K, Tsushima T, Seno Y, Tsugawa M, Takenaka T, Hamasuna R, Fujimoto N, Sho T, Takahashi K, Inatomi H, Takahashi N, Ikei Y, Hayami H, Yamane T, Nakagawa M, Kariya S, Arima T. The nationwide study of bacterial pathogens associated with urinary tract infections conducted by the Japanese Society of Chemotherapy. J Infect Chemother2011 Feb;17(1):126-38.
  5. Matsui H, Hanaki H, Inoue M, Akama H, Nakae T, Sunakawa K, Omura S. Development of an Immunochromatographic Strip for Simple Detection of Penicillin Binding Protein 2'. Clin Vaccine Immunol. 2011 Feb;18(2):248-53.

2010

  1. Sakai F, Hanaki H, Barada K, Hirao Y, Inamatsu T, Nakae T, Sunakawa K. A 25-year trace of methicillin-resistant Staphylococcus aureus dissemination in a geriatric hospital in Japan.  Int J Gen Med. 2010 Dec 9;3:399-405.
  2. Sakai F, Hanaki H, Ikeda-Dantsuji Y, Hirao Y, Nonoyama M, Iwata S, Sato Y, Akita H, Nakae T, Sunakawa K. Trends in empirical chemotherapy of bacterial meningitis in children aged more than 4 months in Japan: a survey from 1997 through 2008. J Infect Chemother. 2010 Sep 29.
  3. Kobayashi Y, Ichioka M, Hirose T, Nagai K, Matsumoto A, Matsui H, Hanaki H, Masuma R, Takahashi Y, Omura S, Sunazuka T. Bottromycin derivatives: efficient chemical modifications of the ester moiety and evaluation of anti-MRSA and anti-VRE activities. Bioorg Med Chem Lett. 2010 Oct 15;20(20):6116-20.
  4. Ikeda-Dantsuji Y, Hanaki H, Sakai F, Tomono K, Takesue Y, Honda J, Nonomiya Y, Suwabe A, Nagura O, Yanagihara K, Mikamo H, Fukuchi K, Kaku M, Kohno S, Yanagisawa C, Nakae T, Yoshida K, Niki Y. Linezolid-resistant Staphylococcus aureus isolated from 2006 through 2008 at six hospitals in Japan. J Infect Chemother. 2011 Feb;17(1):45-51.
  5. Ikeda S, Hanaki H, Yanagisawa C, Ikeda-Dantsuji Y, Matsui H, Iwatsuki M, Shiomi K, Nakae T, Sunakawa K, Omura S. Identification of the active component that induces vancomycin resistance in MRSA. J Antibiot (Tokyo)2010 Sep;63(9):533-8.
  6. Ishihara K, Shimokubo N, Sakagami A, Ueno H, Muramatsu Y, Kadosawa T, Yanagisawa C, Hanaki H, Nakajima C, Suzuki Y, Tamura Y. Occurrence and molecular characteristics of methicillin-resistant Staphylococcus aureus and methicillin-resistant Staphylococcus pseudintermedius in an academic veterinary hospital. Appl Environ Microbiol2010 Aug;76(15):5165-74.
  7. Higuchi W, Mimura S, Kurosawa Y, Takano T, Iwao Y, Yabe S, Razvina O, Nishiyama A, Ikeda-Dantsuji Y, Sakai F, Hanaki H, Yamamoto T. Emergence of the community-acquired methicillin-resistant Staphylococcus aureus USA300 clone in a Japanese child, demonstrating multiple divergent strains in Japan. J Infect Chemother2010 Aug;16(4):292-7.
  8. Higuchi W, Hung WC, Takano T, Iwao Y, Ozaki K, Isobe H, Teng LJ, Shimazaki T, Honda A, Higashide M, Hanaki H, Yamamoto T. Molecular characteristics of the Taiwanese multiple drug-resistant ST59 clone of Panton-Valentine leucocidin-positive community-acquired methicillin-resistant Staphylococcus aureus from pediatric cellulitis.  J Infect Chemother. 2010. Apr;16(2):144-9.

2009

  1. Koichiro Yoshida, Hisashi Shoji, Hideaki Hanaki, Chie Yanagisawa, Yurika Ikeda-Dantsuji, Kunihiko Fukuchi, Mitsuru Adachi and Yoshihito Niki. Linezolid-resistant methicillin-resistant Staphylococcus aureus isolated after long-term, repeated use of linezolid. J Infect Chemother. 15:417-419.2009.
  2. Hiroshi Sakata, Yoshikiyo Toyonaga, Yoshitake Sato, Hideaki Hanaki, Masato Nonoyama, Tomohiro Oishi and Keisuke Sunakawa. Nationwide survey of the development of drug-resistance in the pediatric field: drug sensitivity of Haemophilus influenzae in Japan. J Infect Chemother. 15:410-413.2009.
  3. Yoshitake Sato, Yoshikiyo Toyonaga, Hideaki Hanaki, Masato Nonoyama, Tomohiro Oishi and Keisuke Sunakawa. Nationwide survey of the development of drug-resistant pathogens in the pediatric field: drug sensitivity of Streptococcus pneumoniae in Japan. J Infect Chemother. 15:402-409.2009.
  4. Niki Y, Hanaki H, Matsumoto T, Yagisawa M, Kohno S, Aoki N, Watanabe A, Sato J, Hattori R, Terada M, Koashi N, Kozuki T, Maruo A, Morita K, Ogasawara K, Takahashi Y, Watanabe J, Takeuchi K, Fujimura S, Takeda H, Ikeda H, Sato N, Niitsuma K, Saito M, Koshiba S, Kaneko M, Miki M, Nakanowatari S, Honda Y, Chiba J, Takahashi H, Utagawa M, Kondo T, Kawana A, Konosaki H, Aoki Y, Ueda H, Sugiura H, Ichioka M, Goto H, Kurai D, Okazaki M, Yoshida K, Yoshida T, Tanabe Y, Kobayashi S, Okada M, Tsukada H, Imai Y, Honma Y, Nishikawa K, Yamamoto T, Kawai A, Kashiwabara T, Takesue Y, Wada Y, Nakajima K, Miyara T, Toda H, Mitsuno N, Sugimura H, Yoshioka S, Kurokawa M, Munekawa Y, Nakajima H, Kubo S, Ohta Y, Mikasa K, Maeda K, Kasahara K, Koizumi A, Sano R, Yagi S, Takaya M, Kurokawa Y, Kusano N, Mihara E, Kuwabara M, Fujiue Y, Ishimaru T, Matsubara N, Kawasaki Y, Tokuyasu H, Masui K, Negayama K, Ueda N, Ishimaru M, Nakanishi Y, Fujita M, Honda J, Kadota J, Hiramatsu K, Aoki Y, Nagasawa Z, Suga M, Muranaka H, Yanagihara K, Fujita J, Tateyama M, Sunakawa K, Totsuka K. Nationwide surveillance of bacterial respiratory pathogens conducted by the Japanese Society of Chemotherapy in 2007: general view of the pathogens' antibacterial susceptibility. J Infect Chemother. 15:156-67.2009.
  5. Yamaguchi Y, Hanaki H, Yanagisawa C, Ikeda-Dantsuji Y, Hashimoto T, Yazaki H, Sugahara K, Yanagisawa T, Kawajiri H, Sato S, Ishizaki A, Tachihara-Sato R, Takahashi Y, Ono T, Kageyama Y, Kawaguchi T, Tamura A, Hagane K, Sunakawa K.  Characterization of beta-lactam antibiotic-induced vancomycin-resistant MRSA (BIVR) in a patient with septicemia during long-term vancomycin administration. J Infect Chemother. 15:274-8. 2009.
  6. Matsui H, Hanaki H, Takahashi K, Yokoyama A, Nakae T, Sunakawa K, Omura S. Rapid detection of vaginal Candida species by newly developed immunochromatography. Clin Vaccine Immunol. 16:1366-8. 2009.
  7. Yanagisawa C, Hanaki H, Matsui H, Ikeda S, Nakae T, Sunakawa K. Rapid Depletion of Free Vancomycin in the Medium in the Presence of beta-lactam Antibiotics and Growth Restoration in beta-lactam-Induced-Vancomycin-Resistant Staphylococcus aureus. Antimicrob Agents Chemother. 53:63-8. 2009.

2008

  1. Sugimura M, Maseda H, Hanaki H, Nakae T. Macrolide Antibiotic-Mediated Down Regulation of MexAB-OprM Efflux Pump Expression in Pseudomonas aeruginosa. Antimicrob Agents Chemother. 52:4141-4.2008.
  2. Sunazuka T, Shudo H, Nagai K, Yoshida K, Yamaguchi Y, Hanaki H, Omura S. 4'''-N-demethylspiramycin derivatives: synthesis and evaluation of effectiveness against drug-resistant bacteria. J. Antibiot., 175-84, 2008.
  3. Y. Niki, H. Hanaki, M. Yagisawa, S. Kohno, N. Aoki, A. Watanabe, J. Sato, R. Hattori, N. Koashi, T. Kozuki, A. Maruo, K. Morita, K. Ogasawara, Y. Takahashi, J. Watanabe, K. Takeuchi, M. Takahashi, H. takeda, H. Ikeda, H. kaneda, K. Niizuma, M. Saito, S. Koshiba, M. Kaneko, S. Itabashi, M. Miki, S. Nakanowatari, Y. Honda, J. Chiba, H. Takahashi, M. Utagawa, H. Nishiya, S. Kawakami, T. Kondo, A. Kawana, H. Konosaki, Y. Aoki, N. Chonahayashi, H. Ueda, H. Sugiura, M. Ichioka, H. Goto, M. Aoshima, M. Okazaki, T. Ozawa, T. Horiuchi, T. Yoshida, H. Tsukada, S. Kobayashi, H. Yoshikawa, Y. Imai, N. Aoki, Y. Honma, Y. Niki, M. Takaya, Y. Kurokawa, N. Kusano, E. Mihara, M. kuwahara, Y. Fujiue, T. Ishimaru, N. Matsubara, Y. Kawasaki, H. Tokuyasu, K. Masui, E. Shimizu, K. Yoneda, K. negayama, N. Ueda, M. Ishimaru, Y. Nakanishi, M. Fujita, J. Honda, J. kadota, K. Hiramatsu, Y. Aoki, Z. Nagasawa, M. suga, H. Muranaka, S. Kohno, K. Yanagihara, J. Fujita, M. Tateyama, K. Totuka. The first nationwide surveillance of bacterial respiratory pathogens conducted by the Japanese Society of Chemotherapy. Part 1: A general view on antibacterial susceptibility. J Infect Chemother. 14:279-290, 2008.
  4. Oshiro T, Nagasawa N, Hanaki H, Ikeda-Dantsuji Y, and Nagayama N. The antagonistic effects of a combination of vancomycin and minocycline on Staphylococcus aureus with heterogeneous resistance to vancomycin. J Infect Chemother. 14:15-22,2008.

2007

  1. Fukumoto A, Yong-Pil Kim, Hanaki H, Shiomi K, Tomoda H, Omura S. Cyslaban, a new potentiator of imipenem activity against methicillin-resistant Staphylococcus aureus, produced by Streptomyces sp. K04-0144. J. Antibiot., 7-10, 2007.
  2. Hanaki H, Koide Y, Yamazaki H, Kubo R, Nakano T, Atsuda K, Sunakawa K. Substrate speciality of HMRZ-86 for beta-lactamase including extended spectrum beta-lactamases (ESBL). J Infect Chemother. 13: 390-395. 2007.
  3. Yanagisawa C, Hanaki H, Nakae N, Sunakawa K. Neutralization of staphylococcal exotoxins by the human-origin intravenous immunoglobulin. J Infect Chemother. 13:368-72.2007.
  4. Sugawara A, Sunazuka T, Hirose T, Nagai K, Yamaguchi Y, Hanaki H, Sharpless KB, Omura S. Design and synthesis via click chemistry of 8,9-anhydroerythromycin A 6,9-hemiketal analogues with anti-MRSA and -VRE activity. Bioorg Med Chem Lett. 2007.
  5. Barada K, Hanaki H, Yamaguchi Y, Ikeda S, Akama H, Nakae T, Inamatsu T, Sunakawa K. Trends of beta-lactam antibiotic susceptibility of blood-borne methicillin- resistant Staphylococcus aureus, MRSA, and its linkage to the staphylococcal cassette chromosome mec (SCCmec) type.  J Infect Chemother. 13:213-8. 2007.
  6. Barada K, Hanaki H, Ikeda S, Yamaguchi Y, Akama H, Nakae T, Inamatsu T, Sunakawa K. Trends in gentamicin and arbekacin susceptibility of the methicillin-resistant Staphylococcus aureus and the genes encoding aminoglycoside-modifying enzymes. J. Infect. Chemother. 3:74-8, 2007.
  7. Hososaka Y, Hanaki H, Endo H, Suzuki Y, Nagasawa Z, Otsuka Y, Nakae T, Sunakawa K. Characterization of oxacillin-susceptible mecA-positive Staphylococcus aureus: a new type of MRSA. J Infect Chemother. 2007 Apr;13(2):79-86. Epub 2007.
  8. Hanaki H, Hososaka Y, Yanagisawa C, Otsuka Y, Nagasawa Z, Nakae T, Sunakawa K. Occurrence of vancomycin intermediate-resistant Staphylococcus aureus in Japan. J. Infect. Chemother.13:118-21, 2007.

2006

  1. Hirose T, Sunazuka T, Noguchi Y, Yamaguchi Y, Hanaki H, K. Barry Sharpless, Omura S. Rapid ‘SAR’via click chemistry: an alkyne-breaking spiramycin is fused with diverse azides to yield new triazole-antibacterial candidates. HETROCYCLES, 69:55-61,2006.
  2. Hososaka Y, Hanaki H, Yanagisawa C, Yamaguchi Y, Matsui H, Nakae T, Iwata S, Hayashi I, Sunakawa K. Nosocomial infection of the β-lactam antibiotic induced vancomycin-resistant Staphylococcus aureus (BIVR). J. Infect. Chemother.12:181-4, 2006.
  3. Colodner R, Reznik B, Gal V, Yamazaki H, Hanaki H, Kubo R. Evaluation of a novel kit Cica-Beta Test 1 for the rapid detection of extended-spectrum beta-lactamases. Eur J Clin Microbial Infect Dis. 25 : 49-51. 2006

2005

  1. Hanaki H, Yamaguchi Y, Harada H, Kawashima S, Kubo R, Kobayashi T, Atsuda K and Sunakawa K. The Synthesis of 7-Substituted-3-dinitrostyryl Cephalorporins and Their Ability for Detecting Extended Spectrum β-Lactamases (ESBLs). J. Antibiot., 58 : 69-73, 2005.
  2. Hanaki H, Yamaguchi Y, Yanagisawa C, Uehara K, Matsui H, Yamaguchi Y, Hososaka Y, Barada K, Sakai H, Itabashi Y, Ikeda S, Atsuda K, Tanaka H, Nagayama A, and Sunakawa K. Investigation of β-lactam antibiotic-induced vancomycin-resistant MRSA (BIVR). J. Infect. Chemother., 11:104-106, 2005.

2004

  1. Hanaki H, Kubo R, Nakano R, Kurihara M, Sunagawa K. Characterization of HMRZ86; novel chemical compound for detecting extended spectrum beta-lactamases. J Antimicrob Chemother., 53 (5) : 888-889. 2004.
  2. Hanaki H, Yamaguchi Y, Nomura S, Nagayama A, Sunakawa K. Rapid detection and differentiation method of VanA, VanB and VanC phenotypes in vancomycin-resistant enterococci. Int. J. Antimicrob. Agents, 23(5):502-505. 2004.
  3. Hanaki H, Yamaguchi Y, Barata K. Sakai H. Sunakawa K. Improved method of detection of “β-lactam antibiotic-induced VCM-resistant MRSA” (BIVR). Int. J. Antimicrob.Agents, 23(3), 310-312. 2004.
  4. Hanaki H, Yamaguchi Y, Nomura S, Haraga I, Nagayama A, Sunakawa K. Method of detecting “ß-lactam antibiotic induced vancomycin resistant MRSA (BIVR)”. Int. J. Antimicrob.Agents, 23(1), 1-5. 2004.

2003

  1. Takayama Y, Hanaki H, Irinoda K, Kokubun H, Yoshida K, and Sunakawa K. Investigation of methicillin-resistant Staphylococcus aureus showing diminished susceptibility isolated from a patient with infective endocarditis. Int. J. Antimicrob. Agents, 22(6): 567-73 2003.

2002

  1. Haraga I., Nomura S., Fukumachi S., Ohjimi H., Hanaki H., Hiramatsu K., Nagayama A. Emergence of vancomycin resistance during therapy against methicillin-resistant Staphylococcus aureus in a burn patient – importance low kevel resistance to vancomycin. Int J Infect Dis., 6(4): 99-113, 2002.

2001

  1. Hanaki H., Nomura S., Akagi H., and Hiramatsu K. Improvement of water-soluble cephalosporin derivatives having antibacterial activity against methicillin- resistant Staphylococcus aureus. Chemotherapy,47(3):170-176,2001.
  2. Aritaka N., Hanaki H., Cui L., and Hiramatsu K. Combination Effect of Vancomycin and beta-Lactams against a Staphylococcus aureus Strain, Mu3, with Heterogeneous Resistance to Vancomycin. Antimicrob Agents Chemother., 45(4):1292-4, 2001.

Up to 2000

  1. Cui L., Murakami H., Kuwahara-Arai K., Hanaki H., and Hiramatsu K. Contribution of a thickened cell wall and its glutamine nonamidated component to the vancomycin resistance expressed by Staphylococcus aureus Mu50. Antimicrob Agents Chemother., 44(9): 2276-85, 2000.
  2. Yamazaki H., Tsuchida Y., Satoh H., Kawashima S., Hanaki H., and Hiramatsu K. Novel cephalosporins 2. Synthesis of 3-heterocyclic-fused thiopyranylthiovinyl cephalosporins and antibacterial activity against methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecalis. J Antibiot.,53(5):551-5,2000.
  3. Yamazaki H., Tsuchida Y., Satoh H., Kawashima S., Hanaki H., and Hiramatsu K. Novel cephalosporins 1. Synthesis of 3-benzothiopyranylthiovinyl cephalosporins and antibacterial activity against methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecalis. J Antibiot., 53(5): 546-50, 2000.
  4. Yamada C., Katayama Y., Murata M., Homma S., Hanaki H., and Hiramatsu K. Survey and properties of methicillin-resistant Staphylococcus aureus (MRSA) in an urban living environment. J. Home Econ., 51(3): 215-221, 2000.
  5. Ohwada A., Sekiya M., Hanaki H., Kuwahara-Arai K., Nagaoka I., Hori S., Tominaga S., Hiramatsu K., and Fukuchi Y. DNA vaccination by meaA sequence evokes an antibacterial immune response against methicillin-resistant Staphylococcus aureus. J. Antimicrob. Chemother., 44: 767-774, 1999.
  6. Cui L., Kasegawa H., Murakami Y., Hanaki H., and Hiramatsu K. Postoperative Toxic Shock Syndrome Caused by A Highly Virulent Methicillin-Resistant Staphylococcus aureus Strain. Scand. J. Infect. Dis., 31(2): 208-209, 1999.
  7. Hiramatsu K., Ito T., and Hanaki H. Mechanisms of methicillin and vancomycin resitance in Staphylococcus aureus. Baillieves Clinical Infection Disease. 5:221-242. 1999.
  8. Hiramatsu K., and Hanaki H. Glycopeptide resistance in staphylococci. Current Opinion Infection Diseases. 11:653-658. 1998.
  9. Hanaki H., Labischinski H., Inaba Y., Kondo N., and Hiramatsu K. Increase in glutamine-non-amidated muropeptides in the peptidoglycan of vancomycin- resistant S. aureus (VRSA) strain Mu50. J. Antimicrob. Chemother. 42:315-320,1998.
  10. Hanaki H., Kuwahara-Arai K., Boyle-Vavra, D., Daum, R. S., Tenover F. C., and Hiramatsu K. Activated cell-wall synthesis is associated with vancomycin resistance in methicillin-resistant Staphylococcus aureus clinical strains Mu3 and Mu50. J. Antimicrob. Chemother. 42: 199-209, 1998.
  11. Hiramatsu, K., Aritaka, N., Hanaki H., Kawasaki, S., Hosoda, Y., Hori, S., Fukuchi,Y., and KobayashI I. Dissemination in Japanese hospitals of strains of Staphylococcus aureus of heterogeneously resistant to vancomycin. Lancet, 350: 1668 -1671, 1997.
  12. Hiramatsu K., Hanaki H., Ino T., Yabuta K., Oguri T., and Tenover F. C. Methicillin- resistant Staphylococcus aureus clinical strain with reduced vancomycin susceptibility. J. Antimicrob. Chemother. 40:135-136, 1997.
  13. Nomura S., Hanaki H., and Nagasawa A. Tazobactam-piperacillin compared with sulbactam- ampicillin, clavulic acid-ticarcillin, sulbactam-cefiperazone, and piperacillin for activity against beta-lactamase-producing bacteria isolated from patients with complicated urinary tract infections. J. Chemother, 9:89-94, 1997.
  14. Nomura S., Hanaki H., Furukawa T., and Unemi N. Antibacterial activity of TOC-50, a new parenteral cephalosporin against penicillin-suseptibility and penicillin-resistant Streptococcus pneumoniae. Chemotherapy, 43:1-5,1996.
  15. Nomura S., Hanaki H., Furukawa T., and Unemi N. In vitro and in vivo antibacterial activities of TOC-50, a new parenteral cephalosporin, against Enterococcus faecalis. Chemotherapy, 42:432-438, 1996.
  16. Nomura S., Hanaki H., and Unemi N. In vitro antibacterial activity of TOC-50, a new parenteral cephalosporin against methicillin-resistant Staphylococcus aureus and Staphylococcus epidermides. Chemotherapy, 42:253-258,1996.
  17. Hanakai H., Akagi H., Nomura S., Unemi N., and Hiramatsu K. Structure-activity relationships of cephalosporin derivatives against methicillin-resistant Staphylococcus aureus and Enterococcus faecalis. J. Antibiot., 49: 402-404, 1996.
  18. Hanaki H., Akagi H., Otani T., and Hiramatsu K. Structure-activity relationships between linkage style at C-3 position and nuclear analogues of C(7)-hydroxyiminoaminothiazole cephalosporins against methicillin-resistant Staphylococcus aureus. J. Infect. Chemother., 2:143-147, 1996.
  19. Hanaki H., Akagi H., Yasui M., and Otani T. Structure-activity relationships of 2-thioisocephem against methicillin- resistant Staphylococcus aureus. J. Antibiot., 48: 901-903, 1995.
  20. Hanaki H., Akagi H., Yasui M., Otani T., Hyoudo A., and Hiramatsu K. TOC-39, a novel parenteral broad-spectrum cephalosporin with excellent activity against methicillin-resistant Staphylococcus aureus. Antimicrob. Agents Chemother, 39: 1120-1126, 1995.
  21. Omura S., Murata M., Hanaki H., Hinotozawa K., Oiwa R., and Tanaka H. Phosalasine, a new herbicidal antibiotic containing Phosphinothricin. Fermentation, isolation, biological activity and mechanism of action. J. Antibiot. 829-835,1984. 

Reviews

in English

  1. Hiramatsu K., Ito T., and Hanaki H. Methicillin and vancomycin resitance in Staphylococcus aureus. Proceeding of the 12 th SB Kurhaus Workshop on Infection Diseases "Staphylococcus aureus" March 12,1999
  2. Hanaki H., and Hiramatsu K. Antibiotic resistance methods and protocols. Detection methods of glycopeptide-resistant Staphylococcus aureus. Part 1-9. In:Stephen H. Gillespie, editor. Susceptibility test. Methods in Molecular Medicine TM/48. New Jersey: Humana Press. p85-91. 2000.
  3. Hanaki H., and Hiramatsu K. Antibiotic resistance methods and protocols. Detection methods of glycopeptide-resistant Staphylococcus aureus. Part 1-10. In:Stephen H. Gillespie, editor. Susceptibility test. Methods in Molecular Medicine TM/48. New Jersey: Humana Press. p93-101. 2000.